Benzethidine

ATC code

• none

Legal status

• AU: S9 (Prohibited substance)
• BR: Class A1 (Narcotic drugs)^[1]
• CA: Schedule I
• DE: Anlage I (Authorized scientific use only)
• UK: Class A
• US: Schedule I

CAS Number

• 3691-78-9 ^Y

PubChem CID

• 62516

Benzethidine

Clinical data
ATC code	none
Legal status
Legal status	AU: S9 (Prohibited substance) BR: Class A1 (Narcotic drugs)[1] CA: Schedule I DE: Anlage I (Authorized scientific use only) UK: Class A US: Schedule I
Identifiers
IUPAC name ethyl 1-[2-(benzyloxy)ethyl]- 4-phenylpiperidine- 4-carboxylate
CAS Number	3691-78-9 Y
PubChem CID	62516
DrugBank	DB01518 Y
ChemSpider	56290 Y
UNII	X0I74BAR02
KEGG	D12685 Y
ChEMBL	ChEMBL2104234 N
CompTox Dashboard (EPA)	DTXSID50190389
Chemical and physical data
Formula	C23H29NO3
Molar mass	367.489 g·mol−1
3D model (JSmol)	Interactive image
SMILES O=C(OCC)C3(c1ccccc1)CCN(CCOCc2ccccc2)CC3
InChI InChI=1S/C23H29NO3/c1-2-27-22(25)23(21-11-7-4-8-12-21)13-15-24(16-14-23)17-18-26-19-20-9-5-3-6-10-20/h3-12H,2,13-19H2,1H3 Y Key:UVTBZAWTRVBTMK-UHFFFAOYSA-N Y
NY (what is this?)  (verify)

Benzethidine is a 4-phenylpiperidine derivative that is related to the clinically used opioid analgesic drug pethidine (meperidine, or Demerol).^[2]

Benzethidine is not currently used in medicine and is a Class A/Schedule I drug which is controlled under UN drug conventions. It has similar effects to other opioid derivatives, such as analgesia, sedation, nausea and respiratory depression.^[3] In the United States, the drug is a Schedule I Narcotic Controlled Substance with a DEA ACSCN of 9606 and 2014 annual aggregate manufacturing quota of nil.^[4] The most common salt in use is the hydrochloride, free base conversion ratio of 0.910.