Niravoline

Niravoline
Names
	Preferred IUPAC name N-Methyl-2-(3-nitrophenyl)-N-[(1S,2S)-2-(pyrrolidin-1-yl)-2,3-dihydro-1H-inden-1-yl]acetamide
Identifiers
CAS Number	130610-93-4 ;
3D model (JSmol)	Interactive image;
ChEMBL	ChEMBL2105162;
ChemSpider	7996923;
PubChem CID	9821174;
UNII	R8T17Q4LXC;
CompTox Dashboard (EPA)	DTXSID601123055 ;
	InChI InChI=1S/C22H25N3O3/c1-23(21(26)14-16-7-6-9-18(13-16)25(27)28)22-19-10-3-2-8-17(19)15-20(22)24-11-4-5-12-24/h2-3,6-10,13,20,22H,4-5,11-12,14-15H2,1H3/t20-,22-/m0/s1 Key: ZSDAQBWGAOKTSI-UNMCSNQZSA-N;
	SMILES CN([C@@H]1[C@H](CC2=CC=CC=C12)N3CCCC3)C(=O)CC4=CC(=CC=C4)[N+](=O)[O-];
Properties
Chemical formula	C22H25N3O3
Molar mass	379.460 g·mol−1
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). Infobox references

Niravoline, also known as RU-51599, is a chemical compound with the formula C
₂₂H
₂₅N
₃O
₃.^[1] It has diuretic and aquaretic effects and has been studied for its potential use for cerebral edema^[2] and cirrhosis.^[3]

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It exerts its pharmacological effect as a κ-opioid receptor agonist.^[4] The drug produces hallucinogenic effects at high doses in humans.^[5]^[6]

References