7-OH-DPAT
From Wikipedia, the free encyclopedia
| Names | |
|---|---|
| IUPAC name | |
| Systematic IUPAC name
7-(Dipropylamino)-5,6,7,8-tetrahydronaphthalen-2-ol[1] | |
| Identifiers | |
3D model (JSmol) |
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| Abbreviations | 7-OH-DPAT |
| ChEMBL | |
| ChemSpider | |
| MeSH | 7-Hydroxy-2-N,N-dipropylaminotetralin |
PubChem CID |
|
| UNII | |
CompTox Dashboard (EPA) |
|
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| Properties | |
| C16H25NO | |
| Molar mass | 247.382 g·mol−1 |
| log P | 3.653 |
| Acidity (pKa) | 10.389 |
| Basicity (pKb) | 3.608 |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
| |
7-OH-DPAT is a synthetic compound that acts as a dopamine receptor agonist with reasonable selectivity for the D3 receptor subtype,[2][3][4] and low affinity for serotonin receptors, unlike its structural isomer 8-OH-DPAT.[5][6][7] 7-OH-DPAT is self-administered in several animal models, and is used to study its addiction effects to cocaine.[8][9][10][11][12]
