Spiroxatrine

Chemical compound From Wikipedia, the free encyclopedia

Spiroxatrine (Spiroxamide, R5188) is a drug which acts as a selective antagonist at both the 5-HT1A receptor and the α2C adrenergic receptor.[1] It is an analog of spiperone and also has some dopamine antagonist effects and a relatively weak opioid action.[2][3]

Quick facts Names, Identifiers ...
Spiroxatrine
Names
IUPAC name
8-(2,3-Dihydro-1,4-benzodioxin-2-ylmethyl)-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one
Identifiers
3D model (JSmol)
ChEMBL
ChemSpider
MeSH Spiroxatrine
UNII
  • InChI=1S/C22H25N3O3/c26-21-22(25(16-23-21)17-6-2-1-3-7-17)10-12-24(13-11-22)14-18-15-27-19-8-4-5-9-20(19)28-18/h1-9,18H,10-16H2,(H,23,26) checkY
    Key: JVGBTTIJPBFLTE-UHFFFAOYSA-N checkY
  • O=C2NCN(c1ccccc1)C23CCN(CC3)CC4Oc5ccccc5OC4
Properties
C22H25N3O3
Molar mass 379.460 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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