List of keratins

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The first sequences of keratins revealed that keratins could be grouped into two categories based on their sequence homologies.[1][2] These two groups of keratins were named as type I and type II keratins.[2] These two categories also represent the first two categories of the superfamily of intermediate filament proteins.

Keratins in this table are classified in the first two columns according to the nomenclature established in 2006.[3] Other names previously used are listed in columns 3 and 4.

Human epithelial keratins

Protein name[3]Gene name[3]Other protein nameOther gene name
K9KRT9Ka9
K10KRT10Ka10
K12KRT12Ka12
K13KRT13Ka13
K14KRT14Ka14
K15KRT15Ka15
K16KRT16Ka16
K17KRT17Ka17
K18KRT18Ka18
K19KRT19Ka19
K20KRT20Ka20
K23KRT23Ka23
K24KRT24Ka24
K25KRT25Ka38, K25irs1, K10C, hIRSa1KRT25A
K26KRT26Ka39, K25irs2, K10D
K27KRT27Ka40, K25irs3, K10B, hIRSa3.1
K28KRT28Ka41, K25irs4, hIRSa2

Human hair keratins

Protein name[3]Gene name[3]Other protein nameOther gene name
K31KRT31Ka25, Ha1KRTHA1
K32KRT32Ka26, Ha2KRTHA2
K33aKRT33AKa27, Ha3-IKRTHA3A
K33bKRT33BKa28, Ha3-IIKRTHA3B
K34KRT34Ka29, Ha4KRTHA4
K35KRT35Ka30, Ha5KRTHA5
K36KRT36Ka31, Ha6KRTHA6
K37KRT37Ka32, Ha7KRTHA7
K38KRT38Ka33, Ha8KRTHA8
K39KRT39Ka35
K40KRT40Ka36

Nonhuman hair/epithelial keratins

Protein name[3]Gene name[3]Other protein nameOther gene name
K41 chimp, gorilla, dog[4]KRT41 chimp, gorilla, dog; KRT41P man, horseφhHaA, Ka34P man
K42 mouse, ratKRT42 mouse, rat; KRT42P manKa22 mouse, rat, K17n mouse, rat

Human keratin pseudogenes

Protein name[3]Gene name[3]Other protein nameOther gene name
KRT221PφhHaB
KRT222PφKRTI, Ka21P
KRT223PφKRTJ, Ka37P

Type II keratins

See also

References

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