List of Schedule I controlled substances (U.S.)
From Wikipedia, the free encyclopedia
This is the list of Schedule I controlled substances in the United States as defined by the Controlled Substances Act.[1] The following findings are required for substances to be placed in this schedule:[2]
- The drug or other substance has a high potential for abuse.
- The drug or other substance has no current accepted medical use in treatment in the United States.
- There is a lack of accepted safety for use of the drug or other substance under medical supervision.
The complete list of Schedule I substances is as follows.[1] The Administrative Controlled Substances Code Number for each substance is included.
Opioids
Opium derivatives
| ACSCN | Drug |
|---|---|
| 9319 | Acetorphine[4][note 1] |
| 9051 | Acetyldihydrocodeine[4][note 1] |
| 9052 | Benzylmorphine[4][note 1] |
| 9070 | Codeine methylbromide[4][note 1] |
| 9053 | Codeine-N-Oxide[4][note 1] |
| 9054 | Cyprenorphine[4][note 1] |
| 9055 | Desomorphine[4][note 1] |
| 9145 | Dihydromorphine[4][note 1] |
| 9335 | Drotebanol[28] |
| 9056 | Etorphine (except hydrochloride salt)[29] |
| 9200 | Heroin[4][note 1] |
| 9301 | Hydromorphinol[4][note 1] |
| 9302 | Methyldesorphine[4][note 1] |
| 9304 | Methyldihydromorphine[4][note 1] |
| 9305 | Morphine methylbromide[4][note 1] |
| 9306 | Morphine methylsulfonate[4][note 1] |
| 9307 | Morphine-N-Oxide[4][note 1] |
| 9308 | Myrophine[4][note 1] |
| 9309 | Nicocodeine[4][note 1] |
| 9312 | Nicomorphine[4][note 1] |
| 9313 | Normorphine[4][note 1] |
| 9314 | Pholcodine[4][note 1] |
| 9315 | Thebacon[4][note 1] |
Hallucinogenic or psychedelic substances
| ACSCN | Drug |
|---|---|
| 7249 | α-ET[30] |
| 7391 | 4-bromo-2,5-dimethoxyamphetamine (DOB)[31] |
| 7392 | 2C-B[32] |
| 7396 | 2,5-dimethoxyamphetamine (2,5-DMA)[31] |
| 7399 | DOET[33] |
| 7348 | 2C-T-7[34] |
| 7411 | 4-methoxyamphetamine (PMA)[31] |
| 7401 | 5-methoxy-3,4-methylenedioxyamphetamine (MMDA)[4][note 1] |
| 7395 | 4-methyl-2,5-dimethoxyamphetamine (DOM; STP)[4][note 1] |
| 7400 | 3,4-methylenedioxyamphetamine (MDA)[4][note 1] |
| 7405 | 3,4-methylenedioxymethamphetamine (MDMA)[35] |
| 7404 | 3,4-methylenedioxy-N-ethylamphetamine (MDEA; MDE)[36] |
| 7402 | N-hydroxy-3,4-methylenedioxyamphetamine (N-hydroxy MDA)[36] |
| 7390 | 3,4,5-trimethoxyamphetamine (TMA)[4][note 1] |
| 7431 | 5-MeO-DMT[37] |
| 7432 | Alpha-methyltryptamine (αMT)[38] |
| 7433 | Bufotenine[4][note 1] |
| 7434 | Diethyltryptamine (DET)[4][note 1] |
| 7435 | Dimethyltryptamine (DMT)[4][note 1] |
| 7439 | 5-methoxy-N,N-diisopropyltryptamine (5-MeO-DIPT)[38] |
| 7260 | Ibogaine[4][note 1] |
| 7315 | Lysergic acid diethylamide (LSD)[4][note 1] |
| 7360 | Marijuana[4][note 1][note 2][39] |
| 7381 | Mescaline[4][note 1] |
| 7286 | MXE |
| 7374 | Parahexyl[40] |
| 7415 | Peyote[4][note 1] |
| 7482 | N-ethyl-3-piperidyl benzilate[4][note 1] |
| 7484 | N-methyl-3-piperidyl benzilate[4][note 1] |
| 7437 | Psilocybin[4][note 1] |
| 7438 | Psilocin[4][note 1] |
| 7370 | Tetrahydrocannabinol (THC)[note 2][39] |
| 7455 | Ethylamine analog of phencyclidine (Eticyclidine; PCE) |
| 7458 | Pyrrolidine analog of phencyclidine (PCPy) |
| 7470 | Thiophene analog of phencyclidine (TCP) |
| 7473 | 1-[1-(2-thienyl)cyclohexyl]pyrrolidine (TCPy) |
| 1239 | 4-Chloromethcathinone |
| 1259 | 3-Methylmethcathinone (3-MMC) |
| 1248 | 4-Methylmethcathinone (Mephedrone) |
| 7535 | 3,4-methylenedioxypyrovalerone (MDPV) |
| 7509 | 2-(2,5-Dimethoxy-4-ethylphenyl)ethanamine (2C-E) |
| 7508 | 2-(2,5-Dimethoxy-4-methylphenyl)ethanamine (2C-D) |
| 7519 | 2-(4-Chloro-2,5-dimethoxyphenyl)ethanamine (2C-C) |
| 7518 | 2-(4-Iodo-2,5-dimethoxyphenyl)ethanamine (2C-I) |
| 7385 | 2-[4-(Ethylthio)-2,5-dimethoxyphenyl]ethanamine (2C-T-2) |
| 7532 | 2-[4-(Isopropylthio)-2,5-dimethoxyphenyl]ethanamine (2C-T-4) |
| 7517 | 2-(2,5-Dimethoxyphenyl)ethanamine (2C-H) |
| 7521 | 2-(2,5-Dimethoxy-4-nitro-phenyl)ethanamine (2C-N) |
| 7524 | 2-(2,5-Dimethoxy-4-(n)-propylphenyl)ethanamine (2C-P) |
| 7536 | 2-(4-Bromo-2,5-dimethoxyphenyl)-N-(2-methoxybenzyl)
ethanamine (25B-NBOMe) |
| 7537 | 2-(4-Chloro-2,5-dimethoxyphenyl)-N-(2-methoxybenzyl)
ethanamine (25C-NBOMe) |
| 7538 | 2-(4-Iodo-2,5-dimethoxyphenyl)-N-(2-methoxybenzyl)
ethanamine (25I-NBOMe) |
| 7540 | 3,4-Methylenedioxy-N-methylcathinone (methylone) |
Depressants
| ACSCN | Drug |
|---|---|
| 2010 | gamma-Hydroxybutyric acid (GHB; sodium oxybate; sodium oxybutyrate) except formulations in an FDA-approved drug product are Schedule III |
| 2572 | Mecloqualone |
| 2565 | Methaqualone |
Stimulants
| ACSCN | Drug |
|---|---|
| 1219 | Amineptine |
| 1585 | Aminorex (aminoxaphen; 2-amino-5-phenyl-2- oxazoline; or 4,5-dihydro-5-phenly-2-oxazolamine) |
| 7493 | N-benzylpiperazine (some other names: BZP; 1-benzylpiperazine) |
| 1235 | Cathinone |
| 1503 | Fenethylline |
| 1476 | 4-Fluoroamphetamine |
| 1237 | Methcathinone (Some other names: 2-(methylamino)-propiophenone; alpha-(methylamino)propiophenone; 2-(methylamino)-1-phenylpropan-1-one; alpha-N-methylaminopropiophenone; monomethylpropion; ephedrone; N-methylcathinone; methylcathinone; AL-464; AL-422; AL-463 and UR1432), its salts, optical isomers and salts of optical isomers |
| 1590 | (±)-cis-4-methylaminorex |
| 1475 | N-ethylamphetamine |
| 1480 | N,N-dimethylamphetamine (also known as N,N-alpha-trimethyl-benzeneethanamine; N,N-alpha-trimethylphenethylamine) |
| 7543 | N-Ethylpentylone (ephylone, N-1-(1,3-benzodioxol-5-yl)-2-(ethylamino)-1-pentanone))[41] |
| 7246 | N-Ethylhexedrone[42] (hexen) |
| 7544 | alpha-Pyrrolidinohexanophenone (α-PHP)[42] |
| 7551 | alpha-Pyrrolidinoisohexanophenone (also known as α-PHiP; α-PiHP) [43] |
| 7245 | 4-Methyl-alpha-ethylaminopentiophenone (4-MEAP)[42] |
| 7446 | 4'-Methyl-alpha-pyrrolidinohexiophenone (MPHP)[42] |
| 7548 | alpha-Pyrrolidinoheptaphenone (PV8)[42] |
| 7443 | 4-Chloro-alpha-pyrrolidinovalerophenone (4-chloro-α-PVP)[42] |
| 1233 | 3-Fluoro-N-methylcathinone (3-FMC; 1-(3-fluorophenyl)-2-(methylamino)propan-1-one) |
| 1238 | 4-Fluoro-N-methylcathinone (4-FMC, flephedrone, 1-(4-fluorophenyl)-2-(methylamino)propan-1-one) |
| 1246 | Pentedrone (α-methylaminovalerophenone, 2-(methylamino)-1-phenylpentan-1-one) |
| 1249 | 4-Methyl-N-ethylcathinone (4-MEC, 2-(ethylamino)-1-(4-methylphenyl)propan-1-one) |
| 1258 | Naphyrone (naphthylpyrovalerone; 1-(naphthalen-2-yl)-2-(pyrrolidin-1-yl)pentan-1-one) |
| 7498 | 4-Methyl-alphapyrrolidinopropiophenone (4-MePPP, MePPP, 4-methyl-α-pyrrolidinopropiophenone,1-(4-methylphenyl)-2-(pyrrolidin-1-yl)-propan-1-one) |
| 7541 | Butylone (bk-MBDB, 1-(1,3-benzodioxol-5-yl)-2-(methylamino)butan-1-one) |
| 7542 | Pentylone (bk-MBDP, 1-(1,3-benzodioxol-5-yl)-2-(methylamino)pentan-1-one) |
| 7545 | alpha-pyrrolidinopentiophenone (α-PVP, α-pyrrolidinovalerophenone, 1-phenyl-2-(pyrrolidin-1-yl)pentan-1-one) |
| 7546 | alpha-pyrrolidinobutiophenone (α-PBP, 1-phenyl-2-(pyrrolidin-1-yl)butan-1-one) |
| 1227 | Mesocarb |
Cannabimimetic agents
| ACSCN | Drug |
|---|---|
| 7297 | 5-(1,1-dimethylheptyl)-2-[(1R,3S)-3-hydroxycyclohexyl]-phenol (CP-47,497) |
| 7298 | 5-(1,1-dimethyloctyl)-2-[(1R,3S)-3-hydroxycyclohexyl]-phenol (cannabicyclohexanol or CP-47,497 C8-homolog) |
| 7118 | 1-pentyl-3-(1-naphthoyl)indole (JWH-018 and AM678) |
| 7173 | 1-butyl-3-(1-naphthoyl)indole (JWH-073) |
| 7019 | 1-hexyl-3-(1-naphthoyl)indole (JWH-019) |
| 7200 | 1-[2-(4-morpholinyl)ethyl]-3-(1-naphthoyl)indole (JWH-200) |
| 6250 | 1-pentyl-3-(2-methoxyphenylacetyl)indole (JWH-250) |
| 7081 | 1-pentyl-3-[1-(4-methoxynaphthoyl)]indole (JWH-081) |
| 7122 | 1-pentyl-3-(4-methyl-1-naphthoyl)indole (JWH-122) |
| 7398 | 1-pentyl-3-(4-chloro-1-naphthoyl)indole (JWH-398) |
| 7201 | 1-(5-fluoropentyl)-3-(1-naphthoyl)indole (AM2201) |
| 7694 | 1-(5-fluoropentyl)-3-(2-iodobenzoyl)indole (AM694) |
| 7104 | 1-pentyl-3-[(4-methoxy)-benzoyl]indole (SR-19 and RCS-4) |
| 7008 | 1-cyclohexylethyl-3-(2-methoxyphenylacetyl)indole 7008 (SR-18 and RCS-8) |
| 7203 | 1-pentyl-3-(2-chlorophenylacetyl)indole (JWH-203) |
| 7144 | (1-pentyl-1H-indol-3-yl)(2,2,3,3-tetramethylcyclopropyl)methanone, its optical, positional, and geometric isomers, salts and salts of isomers (UR-144, 1-pentyl-3-(2,2,3,3-tetramethylcyclopropoyl)indole) |
| 7011 | [1-(5-fluoro-pentyl)-1H-indol-3-yl](2,2,3,3-tetramethylcyclopropyl)methanone, its optical, positional, and geometric isomers, salts and salts of isomers (5-fluoro-UR-144, 5-F-UR-144, XLR-11, 1-(5-fluoro-pentyl)-3-(2,2,3,3-tetramethylcyclopropoyl)indole) |
| 7048 | N-(1-adamantyl)-1-pentyl-1H-indazole-3-carboxamide, its optical, positional, and geometric isomers, salts and salts of isomers (APINACA, AKB-48) |
| 7222 | Quinolin-8-yl 1-pentyl-1H-indole-3-carboxylate (QUPIC, PB-22)[44] |
| 7225 | Quinolin-8-yl 1-(5-fluoropentyl)-1H-indole-3-carboxylate (5-fluoro-PB-22; 5F-PB-22)[44] |
| 7012 | N-(1-amino-3-methyl-1-oxobutan-2-yl)-1-(4-fluorobenzyl)-1H-indazole-3-carboxamide (AB-FUBINACA)[44] |
| 7035 | N-(1-amino-3,3-dimethyl-1-oxobutan-2-yl)-1-pentyl-1H-indazole-3-carboxamide (ADB-PINACA)[44] |
| 7031 | N-(1-amino-3-methyl-1-oxobutan-2-yl)-1-(cyclohexylmethyl)-1H-indazole-3-carboxamide (AB-CHMINACA)[45] |
| 7023 | N-(1-amino-3-methyl-1-oxobutan-2-yl)-1-pentyl-1H-indazole-3-carboxamide (AB-PINACA)[45] |
| 7024 | [1-(5-fluoropentyl)-1H-indazol-3-yl](naphthalen-1-yl)methanone (THJ-2201)[45] |
| 7034 | 2-(1-(5-Fluoropentyl)-1H-indazole-3-carboxamido)-3,3-dimethylbutanoate (5F-ADB, 5F-MDMB-PINACA)[46] |
| 7033 | Methyl 2-(1-(5-fluoropentyl)-1H-indazole-3-carboxamido)-3-methylbutanoate (5F-AMB)[46] |
| 7049 | N-(Adamantan-1-yl)-1-(5-fluoropentyl)-1H-indazole-3-carboxamide (5F-APINACA, 5F-AKB48)[46] |
| 7010 | N-(1-Amino-3,3-dimethyl-1-oxobutan-2-yl)-1-(4-fluorobenzyl)-1H-indazole-3-carboxamide (ADB-FUBINACA)[46] |
| 7042 | Methyl 2-(1-(cyclohexylmethyl)-1H-indole-3-carboxamido)-3,3-dimethylbutanoate (MDMB-CHMICA, MMB-CHMINACA)[46] |
| 7020 | Methyl 2-(1-(4-fluorobenzyl)-1H-indazole-3-carboxamido)-3,3-dimethylbutanoate (MDMB-FUBINACA)[46] |
| 7032 | N-(1-amino-3,3-dimethyl-1-oxobutan-2-yl)-1-(cyclohexylmethyl)-1H-indazole-3-carboxamide (MAB-CHMINACA; ADB-CHMINACA)[47] |
| 7036 | ethyl 2-(1-(5-fluoropentyl)-1H-indazole-3-carboxamido)-3,3-dimethylbutanoate (5F-EDMB-PINACA)[48] |
| 7041 | methyl 2-(1-(5-fluoropentyl)-1H-indole-3-carboxamido)-3,3-dimethylbutanoate (5F-MDMB-PICA)[48] |
| 7047 | N-(adamantan-1-yl)-1-(4-fluorobenzyl)-1H-indazole-3-carboxamide (FUB-AKB48; FUB-APINACA; AKB48 N-(4-FLUOROBENZYL))[48] |
| 7083 | 1-(5-fluoropentyl)-N-(2-phenylpropan-2-yl)-1H-indazole-3-carboxamide (5F-CUMYL-PINACA; SGT-25)[48] |
| 7014 | (1-(4-fluorobenzyl)-1H-indol-3-yl)(2,2,3,3-tetramethylcyclopropyl) methanone (FUB-144)[48] |
| 7021 | Methyl 2-(1-(4-fluorobenzyl)-1Hindazole-3-carboxamido)-3-methylbutanoate (FUB–AMB, MMB– FUBINACA, AMB–FUBINACA) |
| 7025 | 5F-AB-PINACA (N-(1-amino-3-methyl-1-oxobutan-2-yl)-1-(5-fluoropentyl)-1H-indazole-3-carboxamide) |
| 7044 | MMB-CHMICA (AMB-CHMICA, methyl 2-(1-(cyclohexylmethyl)-1H-indole-3-carboxamido)-3-methylbutanoate) |
| 7085 | 5F-CUMYL-P7AICA (1-(5-fluoropentyl)-N-(2-phenylpropan-2-yl)-1 H-pyrrolo[2,3-b]pyridine-3-carboxamide) |
| 7089 | 4-CN-CUMYL-BUTINACA (1-(4-cyanobutyl)-N-(2-phenylpropan-2-yl)-1H-indazole-3-carboxamide, 4-cyano-CUMYL-BUTINACA, 4-CN-CUMYL BINACA, CUMYL-4CN-BINACA, SGT-78) |
| 7221 | NM-2201 (CBL2201, Naphthalen-1-yl 1-(5-fluoropentyl)-1H-indole-3-carboxylate) |
| 7027 | ADB-BUTINACA (N-[(2S)-1-amino-3,3-dimethyl-1-oxobutan-2-yl]-1-butyl-1H-indazole-3-carboxamide)[43] |
See also
Notes
- This substance was expressly scheduled by the Controlled Substances Act on October 27, 1970. The 1974 Federal Register ruling (by Administrator John R. Bartels, Jr.) merely organized its listing in the Code of Federal Regulations.
- This substance was the subject of an executive order on December 19, 2025. The executive order directs the US Attorney General to begin the process of moving it from a Schedule I to a Schedule III drug