CGP-25454A

CAS Number

• 104391-26-6

PubChem CID

• 9819591

ChemSpider

• 7995340

FormulaC₁₅H₂₀ClN₃O₂

CGP-25454A

Identifiers
IUPAC name 4-chloro-5-cyano-N-[2-(diethylamino)ethyl]-2-methoxybenzamide
CAS Number	104391-26-6
PubChem CID	9819591
ChemSpider	7995340
Chemical and physical data
Formula	C15H20ClN3O2
Molar mass	309.79 g·mol−1
3D model (JSmol)	Interactive image
SMILES CCN(CC)CCNC(=O)C1=C(C=C(C(=C1)C#N)Cl)OC
InChI InChI=1S/C15H20ClN3O2/c1-4-19(5-2)7-6-18-15(20)12-8-11(10-17)13(16)9-14(12)21-3/h8-9H,4-7H2,1-3H3,(H,18,20) Key:JEMKCYHUYUPGFN-UHFFFAOYSA-N

CGP-25454A is a drug which acts as an antagonist at presynaptic D₂Sh autoreceptors on dopaminergic nerve terminals, producing stimulant effects at low doses in animal studies due to increased dopamine release, but sedative effects at higher doses due to loss of selectivity and antagonism of postsynaptic D₂ receptors as well.^[1]