2025 Open de Vendée

Country	Player	Rank1	Seed
BEL	Raphaël Collignon	93	1
FRA	Hugo Gaston	105	2
BEL	Alexander Blockx	121	3
ITA	Francesco Passaro	139	4
FRA	Pierre-Hugues Herbert	141	5
EST	Mark Lajal	145	6
NOR	Nicolai Budkov Kjær	155	7
CAN	Alexis Galarneau	180	8

• ¹ Rankings are as of 22 September 2025.^[1]

The following players received wildcards into the singles main draw:

• Geoffrey Blancaneaux
• Mickael Kaouk
• Loann Massard

The following player received entry into the singles main draw using a protected ranking:

• Emil Ruusuvuori

The following player received entry into the singles main draw through the Junior Accelerator programme:

• Mees Röttgering

The following player received entry into the singles main draw through the Next Gen Accelerator programme:

• Henry Searle

The following player received entry into the singles main draw as an alternate:

• Matteo Martineau

The following players received entry from the qualifying draw:

• Rémy Bertola
• Stuart Parker
• Lucas Poullain
• Jelle Sels
• Hamish Stewart
• Nikolay Vylegzhanin

The following player received entry as a lucky loser:

• Robert Strombachs

• Nicolai Budkov Kjær def. Patrick Kypson 6–0, 6–3.

• Grégoire Jacq / Albano Olivetti def. Hamish Stewart / Harry Wendelken 7–6^(7–5), 6–3.