GBLD-345

GBLD-345
Identifiers
	IUPAC name 2-(4-aminophenyl)-3-methoxy-N-[(3-methoxyphenyl)methyl] imidazo[2,1-f]pyridazin-6-amine;
CAS Number	122479-08-7;
PubChem CID	4602899;
ChemSpider	3794457;
UNII	VW8QLT5H8X;
ChEMBL	ChEMBL1339029;
CompTox Dashboard (EPA)	DTXSID301028519 ;
Chemical and physical data
Formula	C21H21N5O2
Molar mass	375.432 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES COC1=CC=CC(CNC(C=C2)=NN3C2=NC(C4=CC=C(N)C=C4)=C3OC)=C1;
	InChI InChI=1S/C21H21N5O2/c1-27-17-5-3-4-14(12-17)13-23-18-10-11-19-24-20(21(28-2)26(19)25-18)15-6-8-16(22)9-7-15/h3-12H,13,22H2,1-2H3,(H,23,25); Key:HQRHGSRWOHGIRI-UHFFFAOYSA-N;
	(verify)

GBLD-345 is an anxiolytic drug used in scientific research, which acts as a non-selective, full-efficacy positive allosteric modulator of the GABA_A receptor. It has similar effects to benzodiazepine drugs, but is structurally distinct and so is classed as a nonbenzodiazepine anxiolytic.^[1]

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Identifiers

IUPAC name 2-(4-aminophenyl)-3-methoxy-N-[(3-methoxyphenyl)methyl] imidazo[2,1-f]pyridazin-6-amine
CAS Number	122479-08-7
PubChem CID	4602899
ChemSpider	3794457
UNII	VW8QLT5H8X
ChEMBL	ChEMBL1339029
CompTox Dashboard (EPA)	DTXSID301028519
Chemical and physical data
Formula	C₂₁H₂₁N₅O₂
Molar mass	375.432 g·mol⁻¹
3D model (JSmol)	Interactive image
SMILES COC1=CC=CC(CNC(C=C2)=NN3C2=NC(C4=CC=C(N)C=C4)=C3OC)=C1
InChI InChI=1S/C21H21N5O2/c1-27-17-5-3-4-14(12-17)13-23-18-10-11-19-24-20(21(28-2)26(19)25-18)15-6-8-16(22)9-7-15/h3-12H,13,22H2,1-2H3,(H,23,25) Key:HQRHGSRWOHGIRI-UHFFFAOYSA-N
(verify)