Fominoben

Trade namesBroncomenal, Deronyl, Finaten, Noleptan, Oleptan, Terion, Tosifar, Tussirama^[1]

CAS Number

• 18053-31-1 ^Y

PubChem CID

• 3407

DrugBank

• DB08968

Fominoben

Clinical data
Trade names	Broncomenal, Deronyl, Finaten, Noleptan, Oleptan, Terion, Tosifar, Tussirama[1]
Identifiers
IUPAC name N-[3-chloro-2-[[methyl-(2-morpholin-4-yl-2-oxoethyl)amino]methyl]phenyl]benzamide
CAS Number	18053-31-1 Y
PubChem CID	3407
DrugBank	DB08968
ChemSpider	3290
UNII	TJ2KK6NYJS
KEGG	D07988
ChEBI	CHEBI:135639
ChEMBL	ChEMBL1697837
CompTox Dashboard (EPA)	DTXSID1023075
ECHA InfoCard	100.038.135
Chemical and physical data
Formula	C21H24ClN3O3
Molar mass	401.89 g·mol−1
3D model (JSmol)	Interactive image
SMILES CN(CC1=C(C=CC=C1Cl)NC(=O)C2=CC=CC=C2)CC(=O)N3CCOCC3
InChI InChI=1S/C21H24ClN3O3/c1-24(15-20(26)25-10-12-28-13-11-25)14-17-18(22)8-5-9-19(17)23-21(27)16-6-3-2-4-7-16/h2-9H,10-15H2,1H3,(H,23,27) Key:KSNNEUZOAFRTDS-UHFFFAOYSA-N

Fominoben is an antitussive agent of the benzanilide class, formerly marketed under the name Noleptan.^[2] It binds poorly to the sigma-1 receptor, a receptor activated by many other antitussives.^[3] It is reported to have respiratory stimulant activity.^[4] Other research has indicated it may be an agonist at the benzodiazepine site of the GABA_A receptor.^[5] It was introduced in Germany in 1973, in Italy in 1979, and in Japan in 1983.^[6]

Adverse effects include appetite suppression, nausea, vomiting, insomnia, irritability, and hallucinations. Rarer side effects include somnolence, dizziness, dry mouth, blurred vision, and urticaria.^[7]