Tolibut

Tolibut, also known as 3-(p-tolyl)-4-aminobutyric acid (or β-(4-methylphenyl)-GABA), is drug that was developed in Russia. It is an analogue of γ-aminobutyric acid (GABA) and is the 4-methyl analogue of phenibut, and is also an analogue of baclofen where the 4-chloro substitution has been replaced with a 4-methyl substitution. Tolibut has been described as possessing analgesic, tranquilizing, and neuroprotective properties. It is not fully clear as to whether the drug was ever approved or used medically in Russia.^[1][2][3][4]

ATC code

• None

CAS Number

• 28311-38-8
  28311-37-7 (HCl)

PubChem CID

• 49344

ChemSpider

• 44852

Quick facts Clinical data, ATC code ...

Tolibut

Clinical data
ATC code	None
Identifiers
IUPAC name 4-Amino-3-(4-methylphenyl)butanoic acid
CAS Number	28311-38-8 28311-37-7 (HCl)
PubChem CID	49344
ChemSpider	44852
UNII	UJ5N9SJ9NL
CompTox Dashboard (EPA)	DTXSID00951003
Chemical and physical data
Formula	C11H15NO2
Molar mass	193.246 g·mol−1
3D model (JSmol)	Interactive image
SMILES CC1=CC=C(C=C1)C(CC(=O)O)CN
InChI InChI=1S/C11H15NO2/c1-8-2-4-9(5-3-8)10(7-12)6-11(13)14/h2-5,10H,6-7,12H2,1H3,(H,13,14) Key:MSZRPURXKHMSFF-UHFFFAOYSA-N

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