2021 Andalucía Challenger

Country	Player	Rank1	Seed
ESP	Roberto Carballés Baena	96	1
SVK	Norbert Gombos	98	2
ESP	Jaume Munar	99	3
ITA	Gianluca Mager	102	4
POR	Pedro Sousa	111	5
JPN	Taro Daniel	118	6
BIH	Damir Džumhur	126	7
RUS	Evgeny Donskoy	128	8

• ¹ Rankings are as of 23 March 2021.^[1]

The following players received wildcards into the singles main draw:

• Leo Borg
• Carlos Gimeno Valero
• Carlos Gómez-Herrera

The following player received entry into the singles main draw using a protected ranking:

• Andrey Kuznetsov

The following players received entry into the singles main draw as alternates:

• Maxime Janvier
• Mario Vilella Martínez
• Elias Ymer

The following players received entry from the qualifying draw:

• Javier Barranco Cosano
• Vít Kopřiva
• Nikolás Sánchez Izquierdo
• Carlos Sánchez Jover

• Gianluca Mager def. Jaume Munar 2–6, 6–3, 6–2.

• Dominic Inglot / Matt Reid def. Romain Arneodo / Hugo Nys 1–6, 6–3, [10–6].