2021 Gran Canaria Challenger II

Country	Player	Rank1	Seed
ESP	Carlos Alcaraz	127	1
ITA	Federico Gaio	133	2
SRB	Nikola Milojević	149	3
SRB	Danilo Petrović	154	4
ITA	Lorenzo Giustino	158	5
ITA	Alessandro Giannessi	163	6
SVK	Filip Horanský	170	7
BEL	Kimmer Coppejans	182	8

• ¹ Rankings as of 22 February 2021.^[1]

The following players received wildcards into the singles main draw:

• Carlos Alcaraz
• Carlos Gimeno Valero
• Nikolás Sánchez Izquierdo

The following player received entry into the singles main draw as an alternate:

• Javier Barranco Cosano

The following players received entry from the qualifying draw:

• Eduard Esteve Lobato
• Filip Cristian Jianu
• Emilio Nava
• Giulio Zeppieri

The following player received entry as a lucky loser:

• Sandro Ehrat

• Carlos Gimeno Valero def. Kimmer Coppejans 6–4, 6–2.

• Enzo Couacaud / Manuel Guinard def. Javier Barranco Cosano / Eduard Esteve Lobato 6–1, 6–4.