2021 Saint Petersburg Challenger II

Country	Player	Rank1	Seed
RUS	Roman Safiullin	164	1
KAZ	Dmitry Popko	183	2
TUR	Cem İlkel	210	3
ROU	Marius Copil	224	4
GER	Rudolf Molleker	226	5
POL	Kacper Żuk	232	6
USA	Christopher Eubanks	239	7
RUS	Teymuraz Gabashvili	249	8

• ¹ Rankings as of 1 March 2021.^[1]

The following players received wildcards into the singles main draw:

• Evgenii Tiurnev
• Vaja Uzakov
• Denis Yevseyev

The following player received entry into the singles main draw as a special exempt:

• Zizou Bergs

The following players received entry into the singles main draw as alternates:

• Jesper de Jong
• Michael Vrbenský

The following players received entry from the qualifying draw:

• Mirza Bašić
• Jiří Lehečka
• Matija Pecotić
• Tim van Rijthoven

• Evgenii Tiurnev def. Kacper Żuk 6–4, 6–2.

• Jesper de Jong / Sem Verbeek def. Konstantin Kravchuk / Denis Yevseyev 6–1, 3–6, [10–5].