2021 Wolffkran Open

Country	Player	Rank1	Seed
AUS	Jordan Thompson	72	1
CZE	Jiří Veselý	77	2
ITA	Andreas Seppi	98	3
GER	Yannick Hanfmann	127	4
GER	Oscar Otte	131	5
CZE	Tomáš Macháč	140	6
USA	Maxime Cressy	143	7
FRA	Quentin Halys	150	8

• ¹ Rankings are as of 18 October 2021.^[1]

The following players received wildcards into the singles main draw:

• Max Hans Rehberg
• Mats Rosenkranz
• Henri Squire

The following player received entry into the singles main draw using a protected ranking:

• Yannick Maden

The following players received entry into the singles main draw as alternates:

• Tobias Kamke
• Vitaliy Sachko

The following players received entry from the qualifying draw:

• Matthias Bachinger
• Jonáš Forejtek
• Julian Lenz
• Otto Virtanen

The following player received entry as a lucky loser:

• Hiroki Moriya

• Oscar Otte def. Lukáš Lacko 6–4, 6–4.

• Andre Begemann / Igor Zelenay def. Marek Gengel / Tomáš Macháč 6–2, 6–4.