2021 Potchefstroom Open II

Country	Player	Rank1	Seed
IND	Prajnesh Gunneswaran	131	1
FRA	Benjamin Bonzi	137	2
SUI	Marc-Andrea Hüsler	148	3
GBR	Liam Broady	191	4
GBR	Jay Clarke	193	5
CAN	Brayden Schnur	209	6
TUR	Cem İlkel	214	7
CAN	Peter Polansky	220	8

• ¹ Rankings are as of 8 February 2021.^[1]

The following players received wildcards into the singles main draw:

• Alec Beckley
• Vaughn Hunter
• Khololwam Montsi

The following players received entry into the singles main draw using protected rankings:

• Jenson Brooksby
• Julien Cagnina

The following player received entry into the singles main draw as an alternate:

• Vít Kopřiva

The following players received entry from the qualifying draw:

• Mirza Bašić
• Jack Draper
• Lucas Miedler
• Ryan Peniston

• Jenson Brooksby def. Teymuraz Gabashvili 2–6, 6–3, 6–0.

• Raven Klaasen / Ruan Roelofse def. Julien Cagnina / Zdeněk Kolář 6–4, 6–4.