2021 Brest Challenger

Country	Player	Rank1	Seed
FRA	Arthur Rinderknech	65	1
USA	Jenson Brooksby	70	2
FRA	Richard Gasquet	74	3
USA	Brandon Nakashima	79	4
ITA	Stefano Travaglia	83	5
FRA	Pierre-Hugues Herbert	97	6
SUI	Henri Laaksonen	99	7
FRA	Hugo Gaston	106	8

• ¹ Rankings are as of 18 October 2021.^[1]

The following players received wildcards into the singles main draw:

• Manuel Guinard
• Arthur Rinderknech
• Luca Van Assche

The following player received entry into the singles main draw as a special exempt:

• Carlos Taberner

The following player received entry into the singles main draw as an alternate:

• Maxime Janvier

The following players received entry from the qualifying draw:

• Kenny de Schepper
• Aleksandr Nedovyesov
• Zsombor Piros
• Alexey Vatutin

The following player received entry as a lucky loser:

• Valentin Royer

• Brandon Nakashima def. João Sousa 6–3, 6–3.

• Sadio Doumbia / Fabien Reboul def. Salvatore Caruso / Federico Gaio 4–6, 6–3, [10–3].