2021 Sánchez-Casal Cup

Country	Player	Rank1	Seed
FRA	Hugo Gaston	116	1
SVK	Alex Molčan	119	2
ESP	Bernabé Zapata Miralles	120	3
BIH	Damir Džumhur	136	4
SRB	Nikola Milojević	141	5
AUS	Marc Polmans	158	6
GER	Cedrik-Marcel Stebe	160	7
CZE	Jiří Lehečka	177	8

• ¹ Rankings are as of 27 September 2021.^[1]

The following players received wildcards into the singles main draw:

• Pablo Llamas Ruiz
• Alejandro Moro Cañas
• Nikolás Sánchez Izquierdo

The following player received entry into the singles main draw as an alternate:

• Adrian Andreev

The following players received entry from the qualifying draw:

• Nicolás Álvarez Varona
• Georgii Kravchenko
• Matteo Martineau
• Yshai Oliel

The following players received entry as lucky losers:

• Oleksii Krutykh
• Álvaro López San Martín

• Dimitar Kuzmanov def. Hugo Gaston 6–3, 6–0.

• Harri Heliövaara / Roman Jebavý def. Nuno Borges / Francisco Cabral 6–4, 6–3.