2021 Cassis Open Provence

Country	Player	Rank1	Seed
FRA	Benjamin Bonzi	94	1
JPN	Yasutaka Uchiyama	123	2
AUS	Christopher O'Connell	126	3
KAZ	Mikhail Kukushkin	129	4
FRA	Lucas Pouille	133	5
FRA	Grégoire Barrère	136	6
AUT	Jurij Rodionov	140	7
GBR	Liam Broady	147	8

• ¹ Rankings are as of 30 August 2021.^[1]

The following players received wildcards into the singles main draw:

• Clément Chidekh
• Arthur Fils
• Luca Van Assche

The following players received entry into the singles main draw as alternates:

• Hugo Grenier
• Tatsuma Ito
• Bernard Tomic
• Yosuke Watanuki

The following players received entry from the qualifying draw:

• Nicolás Jarry
• Hiroki Moriya
• Giovanni Mpetshi Perricard
• Ramkumar Ramanathan

The following players received entry as lucky losers:

• Arthur Cazaux
• Alexis Galarneau
• Laurent Lokoli

• Benjamin Bonzi def. Lucas Pouille 7–6^(7–4), 6–4.

• Sriram Balaji / Ramkumar Ramanathan def. Hans Hach Verdugo / Miguel Ángel Reyes-Varela 6–4, 3–6, [10–6].