2022 Arizona Tennis Classic

Country	Player	Rank1	Seed
FRA	Benoît Paire	53	1
ITA	Lorenzo Musetti	56	2
FRA	Arthur Rinderknech	57	3
GER	Jan-Lennard Struff	58	4
ARG	Sebastián Báez	60	5
FRA	Hugo Gaston	68	6
FIN	Emil Ruusuvuori	70	7
BEL	David Goffin	71	8

• ¹ Rankings are as of 7 March 2022.^[2]

The following players received wildcards into the singles main draw:

• Christopher Eubanks
• Brandon Nakashima
• J. J. Wolf

The following player received entry into the singles main draw using a protected ranking:

• Fernando Verdasco

The following players received entry into the singles main draw as alternates:

• Radu Albot
• Daniel Altmaier
• Liam Broady
• Marco Cecchinato
• Denis Kudla
• Oscar Otte
• Aleksandar Vukic

The following players received entry from the qualifying draw:

• Aleksandar Kovacevic
• Mitchell Krueger
• Mikhail Kukushkin
• Emilio Nava
• Max Purcell
• Gilles Simon

The following player received entry as a lucky loser:

• Mats Moraing

• Denis Kudla def. Daniel Altmaier 2–6, 6–2, 6–3.

• Treat Huey / Denis Kudla def. Oscar Otte / Jan-Lennard Struff 7–6^(12–10), 3–6, [10–6].