2022 Open Città della Disfida
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| 2022 Open Città della Disfida | |
|---|---|
| Date | 11–17 April |
| Edition | 22nd |
| Surface | Clay |
| Location | Barletta, Italy |
| Champions | |
| Singles | |
 Nuno Borges | |
| Doubles | |
| Evgeny Karlovskiy / Evgenii Tiurnev | |
The 2022 Open Città della Disfida was a professional tennis tournament played on clay courts. It was the 22nd edition of the tournament which was part of the 2022 ATP Challenger Tour. It took place in Barletta, Italy between 11 and 17 April 2022.
