2022 Open Bogotá

Country	Player	Rank1	Seed
ARG	Facundo Mena	160	1
ARG	Juan Pablo Ficovich	163	2
BRA	Felipe Meligeni Alves	197	3
ARG	Francisco Comesaña	213	4
AUT	Gerald Melzer	247	5
CHI	Gonzalo Lama	263	6
SRB	Miljan Zekić	276	7
ARG	Gonzalo Villanueva	286	8
USA	Aleksandar Kovacevic	298	9

• ¹ Rankings are as of 27 June 2022.^[1]

The following players received wildcards into the singles main draw:

• Nicolás Buitrago
• Sergio Luis Hernández Ramírez
• Andrés Urrea

The following players received entry from the qualifying draw:

• Mateus Alves
• Blu Baker
• Arklon Huertas del Pino
• Ignacio Monzón
• Naoki Nakagawa
• Matías Zukas

The following player received entry as a lucky loser:

• Mukund Sasikumar

• Juan Pablo Ficovich def. Gerald Melzer 6–1, 6–2.

• Nicolás Mejía / Andrés Urrea def. Ignacio Monzón / Gonzalo Villanueva 6–3, 6–4.