2022 Murcia Open

Country	Player	Rank1	Seed
SVK	Norbert Gombos	112	1
ARG	Juan Manuel Cerúndolo	122	2
AUT	Dennis Novak	140	3
TPE	Tseng Chun-hsin	148	4
ESP	Mario Vilella Martínez	172	5
GER	Maximilian Marterer	192	6
ARG	Marco Trungelliti	194	7
ITA	Andrea Pellegrino	196	8

• ¹ Rankings are as of 21 March 2022.^[1]

The following players received wildcards into the singles main draw:

• Ivan Gakhov
• Carlos Gimeno Valero
• Carlos Sánchez Jover

The following players received entry from the qualifying draw:

• Ulises Blanch
• Miguel Damas
• Michael Geerts
• Oleksii Krutykh
• Daniel Mérida
• Rudolf Molleker

The following player received entry as a lucky loser:

• Christopher Heyman

• Tseng Chun-hsin def. Norbert Gombos 6–4, 6–1.

• Íñigo Cervantes / Oriol Roca Batalla def. Pedro Cachin / Martín Cuevas 6–7^(4–7), 7–6^(7–4), [10–7].