2022 Zagreb Open

Country	Player	Rank1	Seed
AUS	Jordan Thompson	87	1
AUS	Aleksandar Vukic	128	2
AUS	Christopher O'Connell	129	3
BIH	Damir Džumhur	162	4
CZE	Vít Kopřiva	167	5
AUS	Jason Kubler	173	6
ARG	Juan Pablo Ficovich	182	7
ITA	Federico Gaio	183	8

• Rankings are as of 2 May 2022.^[1]

The following players received wildcards into the singles main draw:

• Kalin Ivanovski
• Mili Poljičak
• Dino Prižmić

The following players received entry into the singles main draw as alternates:

• Duje Ajduković
• Attila Balázs
• Riccardo Bonadio

The following players received entry from the qualifying draw:

• Nerman Fatić
• Carlos Gimeno Valero
• Fábián Marozsán
• Filip Misolic
• Maximilian Neuchrist
• Wu Yibing

The following players received entry as lucky losers:

• Tristan Lamasine
• Shang Juncheng
• Zhang Zhizhen

• Filip Misolic def. Mili Poljičak 6–3, 7–6^(8–6).

• Adam Pavlásek / Igor Zelenay def. Domagoj Bilješko / Andrey Chepelev 4–6, 6–3, [10–2].