2022 Sibiu Open

Country	Player	Rank1	Seed
ARG	Federico Coria	71	1
AUT	Filip Misolic	145	2
CZE	Zdeněk Kolář	156	3
ARG	Thiago Agustín Tirante	171	4
ITA	Riccardo Bonadio	174	5
BIH	Damir Džumhur	193	6
BEL	Kimmer Coppejans	200	7
SRB	Nikola Milojević	207	8

• ¹ Rankings are as of 12 September 2022.^[1]

The following players received wildcards into the singles main draw:

• Marius Copil
• Victor Vlad Cornea
• Dragoș Dima

The following player received entry into the singles main draw using a protected ranking:

• Jan Choinski

The following players received entry from the qualifying draw:

• Steven Diez
• Giovanni Fonio
• Ivan Gakhov
• Georgii Kravchenko
• Rudolf Molleker
• Kai Wehnelt

• Nerman Fatić def. Damir Džumhur 6–3, 6–4.

• Ivan Sabanov / Matej Sabanov def. Alexander Erler / Lucas Miedler 3–6, 7–5, [10–4].