2022 Challenger Banque Nationale de Drummondville

Country	Player	Rank1	Seed
ECU	Emilio Gómez	107	1
USA	Michael Mmoh	115	2
CAN	Vasek Pospisil	118	3
ARG	Juan Pablo Ficovich	140	4
FRA	Enzo Couacaud	183	5
FRA	Antoine Escoffier	216	6
CAN	Alexis Galarneau	222	7
CAN	Gabriel Diallo	248	8

• ¹ Rankings are as of November 7, 2022.^[1]

The following players received wildcards into the singles main draw:

• Taha Baadi
• Justin Boulais
• Marko Stakusic

The following player received entry into the singles main draw using a protected ranking:

• Julian Ocleppo

The following player received entry into the singles main draw as an alternate:

• Malek Jaziri

The following players received entry from the qualifying draw:

• Liam Draxl
• Maks Kaśnikowski
• Joshua Lapadat
• Max Hans Rehberg
• Roy Smith
• Kai Wehnelt

The following player received entry as a lucky loser:

• Constantin Frantzen
• Roko Horvat

• Vasek Pospisil def. Michael Mmoh 7–6^(7–5), 4–6, 6–4.

• Julian Cash / Henry Patten def. Arthur Fery / Giles Hussey 6–3, 6–3.