2022 Monterrey Challenger

Country	Player	Rank1	Seed
ESP	Fernando Verdasco	153	1
GBR	Jay Clarke	173	2
TPE	Jason Jung	218	3
GER	Cedrik-Marcel Stebe	222	4
ARG	Juan Pablo Ficovich	227	5
FRA	Maxime Janvier	239	6
IND	Prajnesh Gunneswaran	246	7
FRA	Geoffrey Blancaneaux	247	8

• ¹ Rankings are as of 28 February 2022.^[1]

The following players received wildcards into the singles main draw:

• Milledge Cossu
• Ryan Harrison
• Alex Hernández

The following players received entry into the singles main draw using protected rankings:

• Ulises Blanch
• Li Zhe
• Go Soeda
• Rubin Statham

The following players received entry from the qualifying draw:

• William Blumberg
• Strong Kirchheimer
• Aleksandar Kovacevic
• Naoki Nakagawa
• Sho Shimabukuro
• Evan Zhu

• Fernando Verdasco def. Prajnesh Gunneswaran 4–6, 6–3, 7–6^(7–3).

• Hans Hach Verdugo / Austin Krajicek def. Robert Galloway / John-Patrick Smith 6–0, 6–3.