2022 Pereira Challenger

Country	Player	Rank1	Seed
ARG	Facundo Bagnis	104	1
ARG	Tomás Martín Etcheverry	108	2
PER	Juan Pablo Varillas	119	3
USA	Stefan Kozlov	120	4
ARG	Facundo Mena	181	5
NED	Jesper de Jong	189	6
ARG	Thiago Agustín Tirante	197	7
ARG	Nicolás Kicker	203	8

• ¹ Rankings are as of 21 March 2022.^[1]

The following players received wildcards into the singles main draw:

• Nicolás Barrientos
• Mateo Gómez
• Alejandro González

The following player received entry into the singles main draw as a special exempt:

• Paul Jubb

The following players received entry into the singles main draw as alternates:

• Daniel Dutra da Silva
• Peđa Krstin

The following players received entry from the qualifying draw:

• Elmar Ejupovic
• Juan Sebastián Gómez
• Facundo Juárez
• Yshai Oliel
• Oleg Prihodko
• Roberto Quiroz

The following player received entry as a lucky loser:

• Juan Bautista Torres

• Facundo Bagnis def. Facundo Mena 6–3, 6–0.

• Luis David Martínez / Cristian Rodríguez def. Grigoriy Lomakin / Oleg Prihodko 7–6^(7–2), 7–6^(7–3).