2022 Georgia's Rome Challenger

Country	Player	Rank1	Seed
JPN	Yoshihito Nishioka	101	1
USA	J. J. Wolf	116	2
ECU	Emilio Gómez	151	3
ARG	Juan Pablo Ficovich	163	4
CRO	Borna Gojo	174	5
USA	Michael Mmoh	177	6
USA	Bjorn Fratangelo	196	7
FRA	Enzo Couacaud	206	8

• ¹ Rankings as of June 27, 2022.^[1]

The following players received wildcards into the singles main draw:

• Michael Mmoh
• Govind Nanda
• Sam Riffice

The following player received entry into the singles main draw as a special exempt:

• Juan Pablo Ficovich

The following players received entry into the singles main draw as alternates:

• Hady Habib
• Shintaro Mochizuki

The following players received entry from the qualifying draw:

• Strong Kirchheimer
• Patrick Kypson
• Michail Pervolarakis
• Shang Juncheng
• Ben Shelton
• Donald Young

• Wu Yibing def. Ben Shelton 7–5, 6–3.

• Enzo Couacaud / Andrew Harris def. Ruben Gonzales / Reese Stalder 6–4, 6–2.