2022 Internazionali di Tennis d'Abruzzo

Country	Player	Rank1	Seed
USA	Nicolas Moreno de Alboran	242	1
HUN	Máté Valkusz	264	2
BRA	Daniel Dutra da Silva	266	3
ITA	Matteo Arnaldi	275	4
CAN	Alexis Galarneau	300	5
ARG	Hernán Casanova	305	6
FRA	Mathias Bourgue	307	7
DOM	Nick Hardt	312	8
UKR	Oleksii Krutykh	314	9

• ¹ Rankings are as of 9 May 2022.^[1]

The following players received wildcards into the singles main draw:

• Matteo Arnaldi
• Matteo Gigante
• Francesco Maestrelli

The following players received entry into the singles main draw using protected rankings:

• Jeremy Jahn
• Wu Yibing

The following players received entry into the singles main draw as alternates:

• Filippo Baldi
• Giovanni Fonio

The following players received entry from the qualifying draw:

• Paweł Ciaś
• Davide Galoppini
• Omar Giacalone
• Harold Mayot
• Gian Marco Ortenzi
• Arthur Reymond

The following players received entry as lucky losers:

• Riccardo Balzerani
• Tristan Schoolkate

• Matteo Arnaldi def. Francesco Maestrelli 6–3, 6–7^(7–9), 6–4.

• Dan Added / Hernán Casanova def. Davide Pozzi / Augusto Virgili 6–3, 7–5.