2022 Open d'Orléans

Country	Player	Rank1	Seed
FRA	Corentin Moutet	64	1
FRA	Hugo Gaston	79	2
FRA	Richard Gasquet	85	3
FRA	Quentin Halys	86	4
HUN	Márton Fucsovics	91	5
SVK	Norbert Gombos	101	6
SUI	Henri Laaksonen	125	7
USA	Jack Sock	128	8

• ¹ Rankings are as of 19 September 2022.^[1]

The following players received wildcards into the singles main draw:

• Richard Gasquet
• Harold Mayot
• Corentin Moutet

The following players received entry into the singles main draw as special exempts:

• Adrian Andreev
• Nerman Fatić

The following player received entry into the singles main draw as an alternate:

• Skander Mansouri

The following players received entry from the qualifying draw:

• Ulises Blanch
• Joris De Loore
• Arthur Fils
• Maxime Janvier
• Mats Rosenkranz
• Lukáš Rosol

• Grégoire Barrère def. Quentin Halys 4–6, 6–3, 6–4.

• Nicolas Mahut / Édouard Roger-Vasselin def. Michael Geerts / Skander Mansouri 6–2, 6–4.