Ramosetron

Ramosetron (INN) is a serotonin 5-HT₃ receptor antagonist for the treatment of nausea and vomiting.^[1] Ramosetron is also indicated for a treatment of "diarrhea-predominant irritable bowel syndrome in male and women".^[2] In India it is marketed under the brand name of Ibset.

AHFS/Drugs.comInternational Drug Names

Routes of
administrationBy mouth (ODT), IV

ATC code

• None

Elimination half-life5.8 hours

Quick facts Clinical data, AHFS/Drugs.com ...

Ramosetron

Clinical data
AHFS/Drugs.com	International Drug Names
Routes of administration	By mouth (ODT), IV
ATC code	None
Pharmacokinetic data
Elimination half-life	5.8 hours
Identifiers
IUPAC name (1-Methyl-1H-indol-3-yl)[(5R)-4,5,6,7-tetrahydro-1H-benzimidazol-5-yl]methanone
CAS Number	132036-88-5 Y HCl: 132907-72-3 Y
PubChem CID	108000
IUPHAR/BPS	2301 HCl: 2305
ChemSpider	97112 N
UNII	7ZRO0SC54Y HCl: 9551LHD87E Y
KEGG	D02016 N
ChEMBL	ChEMBL1643895 N
CompTox Dashboard (EPA)	DTXSID0043842
Chemical and physical data
Formula	C17H17N3O
Molar mass	279.343 g·mol−1
3D model (JSmol)	Interactive image
SMILES CN1C=C(C2=CC=CC=C21)C(=O)[C@@H]3CCC4=C(C3)NC=N4
InChI InChI=1S/C17H17N3O/c1-20-9-13(12-4-2-3-5-16(12)20)17(21)11-6-7-14-15(8-11)19-10-18-14/h2-5,9-11H,6-8H2,1H3,(H,18,19)/t11-/m1/s1 N Key:NTHPAPBPFQJABD-LLVKDONJSA-N N
NY (what is this?)  (verify)

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It is only licensed for use in Japan and selected Southeast Asian countries. In Japan it is sold under the trade name Irribow.^[3][4] and in India as Ibset . 'Elsewhere it is commonly sold under the trade name Nasea and in India as Nozia (150 μg/mL injection & 100 μg oral tablet).^[5]