Nantenine

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ATC code
  • none
Nantenine
Clinical data
ATC code
  • none
Identifiers
  • (S)-1,2-Dimethoxy-6-methyl-5,6,6a,7-tetrahydro-4H-benzo[de][1,3]benzodioxolo[5,6-g]quinoline
CAS Number
PubChem CID
ChemSpider
UNII
ChEMBL
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC20H21NO4
Molar mass339.391 g·mol−1
3D model (JSmol)
  • CN1CCC2=CC(=C(C3=C2[C@@H]1CC4=CC5=C(C=C43)OCO5)OC)OC
  • InChI=1S/C20H21NO4/c1-21-5-4-11-7-17(22-2)20(23-3)19-13-9-16-15(24-10-25-16)8-12(13)6-14(21)18(11)19/h7-9,14H,4-6,10H2,1-3H3/t14-/m0/s1 ☒N
  • Key:WSVWKHTVFGTTKJ-AWEZNQCLSA-N ☒N
 ☒NcheckY (what is this?)  (verify)

Nantenine is an alkaloid found in the plant Nandina domestica[1] as well as some Corydalis species.[2] It is an antagonist of both the α1-adrenergic receptor[3] and the serotonin 5-HT2A receptor,[4] and blocks both the behavioral and physiological effects of MDMA in animals.[5]

References

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