Sergolexole

CAS Number

• 108674-86-8 ^Y

PubChem CID

• 60262

UNII

• J6TGA89COP

CompTox Dashboard (EPA)

• DTXSID10148700

Sergolexole

Identifiers
IUPAC name (4-methoxycyclohexyl) (6aR,9R,10aR)-7-methyl-4-propan-2-yl-6,6a,8,9,10,10a-hexahydroindolo[4,3-fg]quinoline-9-carboxylate
CAS Number	108674-86-8 Y
PubChem CID	60262
UNII	J6TGA89COP
CompTox Dashboard (EPA)	DTXSID10148700
Chemical and physical data
Formula	C26H36N2O3
Molar mass	424.585 g·mol−1
3D model (JSmol)	Interactive image
SMILES CC(C)N1C=C2C[C@@H]3[C@H](C[C@H](CN3C)C(=O)OC4CCC(CC4)OC)C5=C2C1=CC=C5
InChI InChI=1S/C26H36N2O3/c1-16(2)28-15-17-13-24-22(21-6-5-7-23(28)25(17)21)12-18(14-27(24)3)26(29)31-20-10-8-19(30-4)9-11-20/h5-7,15-16,18-20,22,24H,8-14H2,1-4H3/t18-,19?,20?,22-,24-/m1/s1 Key:RJBJIKXTJIZONR-FTNAIZGWSA-N

Sergolexole (INNTooltip International Nonproprietary Name; developmental code name LY-281,067) is an ergoline derivative which acts as a selective antagonist of the serotonin 5-HT₂ receptors. It has been used for various research applications, but was never developed for medical use.^[1][2][3]