AH-494

AH-494 is a potent and selective, water-soluble full agonist at the 5-HT₇ serotonin receptor of the imidazolylindole family. It is a close derivative of the known chemical probe 5-Carboxamidotryptamine, as well as of the more lipophilic imidazolylindoles: AGH-107 and AGH-192. It has been shown to exhibit favorable ADMET profile in in vitro assays.^[1]

Other namesAH494

ATC code

• None

CAS Number

• 2172907-22-9 ^N[EPA]

PubChem CID

• 138691364

Quick facts Clinical data, Other names ...

AH-494

Clinical data
Other names	AH494
ATC code	None
Identifiers
IUPAC name 3‐(1‐ethyl‐1H‐imidazol‐5‐yl)‐1H‐indole‐5‐carboxamide
CAS Number	2172907-22-9 N[EPA]
PubChem CID	138691364
ChemSpider	68912051
UNII	7HG7TA6D63
ChEMBL	ChEMBL4469847
CompTox Dashboard (EPA)	DTXSID601336553
Chemical and physical data
Formula	C14H14N4O
Molar mass	254.293 g·mol−1
3D model (JSmol)	Interactive image
SMILES CCN1C=NC=C1C2=CNC3=C2C=C(C=C3)C(=O)N
InChI InChI=1S/C14H14N4O/c1-2-18-8-16-7-13(18)11-6-17-12-4-3-9(14(15)19)5-10(11)12/h3-8,17H,2H2,1H3,(H2,15,19) Key:RXDHCCKYQJNUFV-UHFFFAOYSA-N

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